NxStage prepackaged fluids for acute renal care
NxStage provides a full range of easy-to-use, convenient and economical sterile dialysate fluids that simplify the delivery of intensive care dialysis. NxStage PureFlow™ prepackaged solutions offer significant advantages:
- They are available with bicarbonate or lactate buffers, giving you treatment options.
- NxStage PureFlow Solutions ensure fluid quality, with potential clinical benefits. They meet or exceed AAMI, USP, and European Pharmacopoeia standards. Products are terminally sterilized and pyrogen-free (< 0.25 EU/mL).
- They eliminate the need to install large, complex water purification systems.
- They allow for simple dosing and usage, reducing workload on busy ICU staff.
- Convenient 5-liter bags minimize interventions.

Your choice of solution buffer:
Bicarbonate—The body’s natural buffer; may be suitable for patients with lactic acidosis and/or liver failure. The two-compartment bag with unique peel-seam interface simplifies preparation and mixing.
Lactate—Simplest, most economical solution; no mixing required. Effectiveness for most patients is well-supported in clinical literature.
NxStage PureFlow Solutions for use in acute hemodialysis with the NxStage System One include:
Constituent (mEq/L) |
Lactate Buffer |
Bicarbonate Buffer |
| RFP-204 |
RFP-205 |
RFP-207 |
RFP-400 |
RFP-401 |
RFP-402 |
RFP-453 |
RFP-454 |
| Lactate |
40 |
35 |
45 |
0 |
0 |
0 |
0 |
0 |
| Bicarbonate |
0 |
0 |
0 |
35 |
35 |
35 |
25 |
25 |
| Potassium |
1 |
3 |
1 |
2 |
4 |
0 |
2 |
4 |
| Sodium |
140 |
140 |
140 |
140 |
140 |
140 |
130 |
130 |
| Calcium |
3 |
3 |
3 |
3 |
3 |
3 |
0 |
0 |
| Magnesium |
1 |
1 |
1 |
1 |
1 |
1 |
1.5 |
1.5 |
| Chloride |
105 |
112 |
100 |
111 |
113 |
109 |
108.5 |
110.5 |
| Glucose (mg/dL) |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
NxStage PureFlow Solutions are indicated for use with renal replacement systems that utilize sterile premixed dialysate. They are not indicated for direct infusion.
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