NxStage Announces Closing of $40 Million Debt Financing with Asahi Kasei Kuraray Medical

Friday June 5, 2009

LAWRENCE, Mass., June 5 /PRNewswire-FirstCall/ — NxStage Medical, Inc. (Nasdaq: NXTM), a leading manufacturer of innovative dialysis products, today announced it has completed the closing of its previously announced $40 million debt financing with its strategic alliance partner, Asahi Kasei Kuraray Medical. The Company used approximately $30 million of the proceeds to pay off its entire debt obligation, including prepayment and other transaction fees, owed under its GE credit facility. As a result, NxStage anticipates taking a pre-tax charge of approximately $2 million for the second quarter of 2009 related to prepayment and other transaction fees. The remaining proceeds of approximately $10 million will be used for general operating purposes.

About NxStage Medical

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative products for the treatment of ESRD and acute kidney failure. For more information on NxStage and its products, please visit the company’s website at http://www.nxstage.com.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words anticipate, believe, expect, estimate, plan, and similar expressions are generally intended to identify forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including factors that are discussed in NxStage’s filings with the Securities and Exchange Commission, including the Quarterly Report on Form 10-Q for the quarter ended March 31, 2009. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE NxStage Medical, Inc.

CONTACT:
Kristen K. Sheppard, Esq.
VP, Investor Relations
of NxStage Medical, Inc.
+1-978-332-5923
ksheppard@nxstage.com
Web Site: http://www.nxstage.com