NxStage Medical to Present at Susquehanna Healthcare Conference on March 1

Tuesday February 27, 2007

LAWRENCE, Mass., Feb. 27 /PRNewswire-FirstCall/ — NxStage Medical, Inc. (Nasdaq: NXTM), the manufacturer of the NxStage System One&#153 portable kidney dialysis machine, today announced that Robert Brown, Chief Financial Officer, will participate in the Susquehanna SIGnificant Investment Options in Healthcare Conference. Mr. Brown is scheduled to present an overview of the Company at 8:00 a.m. Eastern Time on March 1, 2007 at The Omni Berkshire Place in New York, NY.

To listen to the audio web cast of the presentation during or after the event, please visit: www.nxstage.com and click on ‘Investor Information’. The replay will be available for 14 days after the event.

Forward-Looking Statements:

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words anticipate, believe, expect, estimate, plan, and similar expressions are generally intended to identify forward-looking statements. Examples of these forward-looking statements include statements as to Mr. Brown’s plans to present at the Susquehanna SIGnificant Investment Options in Healthcare Conference. NxStage specifically disclaims any obligation to do update these forward-looking statements. These forward- looking statements should not be relied upon as representing NxStage’s expectations or beliefs as of any date subsequent to the date of this press release.

About NxStage Medical:

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative dialysis systems for the treatment of end-stage renal disease, or ESRD, and acute kidney failure. For more information on NxStage and its products, please visit the company’s website at www.nxstage.com.

SOURCE NxStage Medical, Inc.

Contact:
Kristen K. Sheppard, Esq.
Vice President, Investor Relations
NxStage Medical Inc. (NXTM)
978/332-5923
Web site: http://www.nxstage.com