NxStage(R) Medical to Report First Quarter 2008 Financial Results on Monday, May 12th

Thursday April 24, 2008

LAWRENCE, Mass., April 24 /PRNewswire-FirstCall/ — NxStage Medical, Inc. (Nasdaq: NXTM), a leading manufacturer of innovative dialysis products, today announced plans to release its financial results for the first quarter 2008 on Monday, May 12, 2008 after the close of the financial markets.

NxStage will also host a conference call at 5:00 p.m. Eastern Time on May 12, 2008 to discuss its first quarter 2008 financial results. To listen to the conference call, please dial 800-295-4740 for domestic callers and 617-614-3925 for international callers. The passcode is 32616701. A replay of the conference call will be available 2 hours after the start of the call through June 12, 2008 by dialing 888-286-8010 (domestic) and 617-801-6888 (international), passcode 13355207. An online archive of the conference call will also be available by accessing the Investor Information section of the company’s website at www.nxstage.com.

About NxStage Medical

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative systems for the treatment of end-stage renal disease, or ESRD, and acute kidney failure. For more information on NxStage and its products, please visit the Company’s website at www.nxstage.com.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words anticipate, believe, expect, estimate, plan, and similar expressions are generally intended to identify forward- looking statements. The forward-looking statements in this release include NxStage’s plan to release its financial results on May 12, 2008. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including, but not limited to, unexpected difficulty in closing the company’s financial books for the quarter and other factors that are discussed in NxStage’s Annual Report on Form 10-K for the year ended December 31, 2007 filed with the SEC. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE NxStage Medical, Inc.

Contact:
Kristen K. Sheppard, Esq.
Vice President, Investor Relations
NxStage Medical Inc. (NXTM)
978/332-5923
Web site: http://www.nxstage.com