The System One

Chronic therapy at home or on the road

The NxStage System One helps makes home therapy more accessible. It is the only truly portable hemodialysis system cleared for home use during the day or overnight. The System One was designed to provide simplicity, flexibility and portability to make home hemodialysis a practical reality, without compromising safety.

Due to NxStage's continuous innovation, patients now have the opportunity to enjoy the clinical and lifestyle benefits of more frequent home hemodialysis.

The System One Difference

Making Dialysis Accessible

The simple interface is easy to learn and use.

Our 24/7 technical support gives you peace of mind while dialyzing, no matter when or where.

Designed for the Home

Simple plumbing connections and standard electrical plug minimize the impact on your home.

Integrated dialysate mixing conserves water usage and fits your lifestyle.

Fitting Your Lifestyle

Portability gives you the freedom to travel or dialyze throughout your home.

Easy-to-use drop-in cartridge allows for easy, wipe-down disinfection after each use.


Talk to your physician today or find a center to experience the NxStage difference.

Indications for Use

The NxStage System One is indicated for the treatment of acute and chronic renal failure or fluid overload using hemofiltration, hemodialysis, and/or ultrafiltration, in an acute or chronic care facility.

The system is also indicated for home hemodialysis, including home nocturnal hemodialysis.

All treatments must be administered under physician’s prescription, and must be performed by a trained and qualified person, considered to be competent in the use of this device by the prescribing physician. A patient should not dialyze alone, regardless of whether they are "trained and qualified."

The NxStage PureFlow SL is an accessory to the NxStage System One that prepares dialysate for use during hemodialysis, as prescribed by the physician. There are no known contraindications.

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