The System One Cycler

Chronic therapy at home or on the road

The NxStage System One helps makes home therapy more accessible. It is the only truly portable hemodialysis system cleared for home use. The System One was designed from the ground up to provide the simplicity, flexibility and portability to make home hemodialysis a practical reality, without compromising safety. It was designed to overcome the challenges of home hemodialysis posed by traditional equipment.

Due to NxStage's continuous innovation, patients now have the chance to enjoy the health benefits of more frequent hemodialysis, either at home with our SL package or on the road with our Express package. The result is an entirely new level of personal freedom.

The System One Difference

Making Dialysis Accessible

The simple interface is easy to learn and use.

Our 24/7 technical support gives you peace of mind while dialyzing, no matter when or where.

Designed for the Home

Simple plumbing connections and standard electrical plug minimize the impact on your home.

Integrated dialysate mixing conserves water usage and fits your lifestyle.

Fitting Your Lifestyle

Portability gives you the freedom to travel or dialyze throughout your home.

Easy-to-use drop-in cartridge allows for easy, wipe-down disinfection after each use.


Talk to your physician today or find a center to experience the NxStage difference.

Indications for Use

The NxStage System One is indicated for the treatment of acute and chronic renal failure or fluid overload using hemofiltration, hemodialysis, and/or ultrafiltration, in an acute or chronic care facility.

The system is also indicated for home hemodialysis, including home nocturnal hemodialysis.

All treatments must be administered under physician’s prescription, and must be performed by a trained and qualified person, considered to be competent in the use of this device by the prescribing physician. A patient should not dialyze alone, regardless of whether they are "trained and qualified."

The NxStage PureFlow SL is an accessory to the NxStage System One that prepares dialysate for use during hemodialysis, as prescribed by the physician. There are no known contraindications.

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