Boston Business Journal Names NxStage(R) Medical Third Fastest Growing Company in Massachusetts

Thursday October 1, 2009

LAWRENCE, Mass., Oct. 1 /PRNewswire-FirstCall/ —NxStage Medical, Inc. (Nasdaq: NXTM), a leading manufacturer of innovative dialysis products, today announced that it has been recognized as the No. 3 Fastest Growing Company in Massachusetts by the Boston Business Journal. This is the third consecutive year that NxStage has been recognized by the Boston Business Journal as one of the fastest growing companies for its list, which this year ranks the Fastest Growing Public Companies by revenue growth from 2006 to 2008.

We are pleased to be recognized by the Boston Business Journal for the rapid growth we have achieved as an innovative, market pioneer, said Jeffrey H. Burbank, Founder and Chief Executive Officer of NxStage Medical, Inc. Our growth can be attributed, in part, to our continued efforts in developing the home hemodialysis market with the industry’s only portable, easy-to-use home hemodialysis machine – the NxStage System One&#153, and our market share gains within the critical care market. We also further strengthened our revenue base through the strategic acquisition of Medisystems┬«, our in-center business, in late 2007.

The NxStage System One is the first truly portable hemodialysis system cleared for home use by the U.S. Food & Drug Administration. Its simplicity and compact size are intended to allow ease-of-use and to give patients the opportunity to travel with their therapy with their doctor’s approval. It plugs into standard electrical outlets and, unlike conventional hemodialysis systems, requires no special infrastructure to operate. Under the guidance of their physician, patients can use the NxStage System One, with their trained partners, where, how and when it best meets their needs, at home or on vacation.

In 2009, NxStage broadened access to its dialysis products beyond the United States for the first time through a distribution agreement that brought the NxStage System One to the U.K. and Ireland. The Company also formed a strategic business alliance with Asahi Kasei Kuraray Medical, a leading medical supply company in Japan.

About NxStage Medical

NxStage Medical, Inc. (Nasdaq: NXTM) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative products for the treatment of end stage renal disease and acute kidney failure. For more information on NxStage and its products, please visit the company’s website at http://www.nxstage.com.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words anticipate, believe, expect, estimate, plan, and similar expressions are generally intended to identify forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including, but not limited to, changes relating to customer demand for NxStage’s System One and other products, changes in market adoption of home daily hemodialysis, market adoption for the System One and other products internationally, and other factors that are discussed in NxStage’s filings with the Securities and Exchange Commission, including the Quarterly Report on Form 10-Q for the quarter ended June 30, 2009. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.

Contact:
Kristen K. Sheppard, Esq.
VP, Investor Relations
ksheppard@nxstage.com

SOURCE NxStage Medical, Inc.