NxStage® Ranked Number 141 on the Fastest Growing Company in North America on Deloitte’s 2011 Technology Fast 500™

Friday October 21, 2011
LAWRENCE, Mass., Oct. 21, 2011 /PRNewswire/ — NxStage Medical, Inc. (Nasdaq:NXTMNews), a leading manufacturer of innovative dialysis products, today announced it ranked 141 on Deloitte’s Technology Fast 500™ ranking of the 500 fastest growing technology, media, telecommunications, life sciences and clean technology companies in North America. Rankings are based on percentage of fiscal year revenue growth during the period from 2006–2010. NxStage Medical, Inc. grew 761 percent during this period.

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NxStage President and Chief Executive Officer, Jeffrey H. Burbank, credits the Company’s significant revenue growth to its success in pioneering the home hemodialysis market with its System One™, the first and only truly portable, easy-to-use home hemodialysis machine, as well as its continued expansion in both the critical care and in-center markets. NxStage’s in-center business, Medisystems, was acquired by NxStage in 2007.

Burbank said, NxStage is honored to be ranked among the country’s most innovative companies for the fourth year in a row. We believe there are significant growth opportunities ahead and that we are well positioned to capitalize on them in a way that continues to advance the quality of care of dialysis patients.

NxStage Medical, like all 2011 Technology Fast 500™ companies, have excelled in fostering innovation and channeling it into spectacular growth — against the backdrop of one of the most challenging economies in history, said Eric Openshaw, vice chairman and U.S. technology, media and telecommunications leader, Deloitte LLP. Deloitte recognizes NxStage Medical for its remarkable accomplishment.

We are pleased to honor NxStage Medical as a 2011 Technology Fast 500 company, said Mark Jensen, managing partner, technology and venture capital services, Deloitte & Touche LLP. As one of the fastest growing tech companies in North America, NxStage Medical has demonstrated excellence in technological innovation, entrepreneurship and rapid growth.

About the NxStage System One

The NxStage System One is the first and only truly portable hemodialysis system cleared for home use by the U.S. Food & Drug Administration (FDA). Its simplicity and revolutionary size (just over a foot tall) are intended to allow convenient use in patients’ homes and give patients the freedom to travel with their therapy. When combined with the NxStage Pureflow SL Dialysis Preparation System, patients are able to further simplify, using ordinary tap water to create dialysis fluid on demand. Unlike conventional hemodialysis systems, the System One requires no special infrastructure to operate. Under the guidance of their physician, patients can use the NxStage System One, with their trained partners, where, how and when it best meets their needs, at home or on vacation.

About NxStage Medical

NxStage Medical, Inc. (Nasdaq:NXTMNews) is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative systems for the treatment of end-stage renal disease, or ESRD, and acute kidney failure. NxStage is leading the development of the home hemodialysis market in the US with the only portable hemodialysis machine, the System One, cleared for home use by the FDA. For more information on NxStage and its products, please visit the company’s website at https://www.nxstage.com/.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words anticipate, believe, expect, estimate, plan, and similar expressions are generally intended to identify forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including factors that are discussed in NxStage’s filings with the Securities and Exchange Commission, including its Quarterly Report on Form 10-Q for the quarter ended June 30, 2011. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.

Media Contacts:
Kristen Sheppard, Esq.
Vice President, Investor Relations
NxStage Medical, Inc.
ir@nxstage.com
978-332-5923